Achievements

We are conducting Open Collaboration actively to improve our research capacities

Long-Acting Injection

  • Depot(Long action injection) image
    Depot(Long action injection)
    Overview
    • A depot, long-acting injection is a specially designed injectable formulation that allows gradual and sustained drug release over an extended period, improving clinical outcomes in patients with low medication adherence.
    Possessed Technologies
    • Microsphere spray-drying technology
    • Microsphere emulsion technology
    • Nano/micro suspension technology
    • In situ gel technology
    • Development of dual-chamber syringe (DCS)
    Distinguishing Point
    • Robust pipeline based on platform technology
    • Global collaboration with partners (Zydus, USA)
    • Possession of facilities and core technologies spanning from research to production
    • Development of exclusive dual-chamber syringe (DCS) for enhanced administration convenience, equipped with automatic filling system

Microsphere Emulsion Technology

  • Microsphere Emulsion Technology image
    Microsphere Emulsion Technology
    Overview
    • Microsphere Emulsion Technology involves dissolving active ingredients and biodegradable polymers in a solvent to prepare O/W or W/O/W emulsions, followed by solvent evaporation, microspheres collection, and freeze-drying to produce controlled-release microspheres.
    Distinguishing Points
    • Reduction of adverse reactions through controlled initial release
    • Ion channel technology enabling stable drug release profiles over target periods
    • Dose reduction by maximizing encapsulation efficiency
    • Holder of microsphere manufacturing patents

Microsphere Spray drying Technology

  • Microsphere Emulsion Technology image
    Microsphere Sray drying Technology
    Overview
    • Microsphere Spray-Drying Technology produces sustained-release microspheres by dissolving active ingredients and biodegradable polymers in a solvent and spray-drying them using an ultrasonic nozzle.
    Distinguishing Points
    • Capability to manufacture uniform-sized sustained-release microspheres
    • Enhanced safety by eliminating the use of organic solvents in the manufacturing process
    • Holder of microsphere manufacturing patents

Dual-Chamber Syringe (DCS) Development

  • Dual-Chamber Syringe (DCS) Development image
    Dual-Chamber Syringe (DCS) Development
    Overview
    • The Dual-Chamber Syringe (DCS) is a pre-filled syringe equipped with two separate chambers-one for the active drug and the other for the diluent—allowing immediate mixing and administration right before injection.
    Distinguishing Points
    • Capability to manufacture uniform-sized sustained-release microspheres
    • Development of exclusive dual-chamber syringe (DCS) for improved administration convenience, equipped with automatic filling system
    • Holder of patents for the DCS device